Pedro A Valdes Hernandez

Pedro A Valdes Hernandez, Ph.D.

Research Assistant Professor

Department: DN-COMMUNITY DENTISTRY
Business Phone: (352) 273-7180

Research Profile

Dr Valdes-Hernandez’s field of expertise is Neuroimaging. He specializes in Medical Image Analysis, Biostatistics, Computational Neuroanatomy, Computational Neurosciences and the principles of Magnetic Resonance Imaging. His work has been focused on 1) the analysis of large multimodal neuroimaging databases [e.g., MRI, (anatomical, functional, diffusion), and brain electrical topographies and tomographies based on EEG and MEG], 2) the theoretical modeling of brain activity and signal/image formation, and 3) experimental testing of several biophysical theories of the brain. Over his career, He has used a great amount of programming (e.g., MATLAB) to apply several statistical methods (e.g., multivariate regression, machine learning algorithms, signal processing, and inference of state-space models) to extract information from multimodal brain images and infer neurobiological processes. He has also performed EEG/fMRI experimentation in both humans and rats. Moreover, with a mindset on the betterment of health and quality of life of society, he has dealt with a variety of different normal and pathological populations covering a wide range of ages (e.g., he has studied children with Epilepsy and older adults with and without chronic pain).

Open Researcher and Contributor ID (ORCID)

0000-0003-2278-0100

Publications

2021
Age Differences in Multimodal Quantitative Sensory Testing and Associations With Brain Volume
Innovation in Aging. 5(3) [DOI] 10.1093/geroni/igab033. [PMID] 34616958.
2021
Arterial blood stealing as a mechanism of negative BOLD response: From the steady-flow with nonlinear phase separation to a windkessel-based model
Journal of Theoretical Biology. 529 [DOI] 10.1016/j.jtbi.2021.110856. [PMID] 34363836.
2021
Chronic oxytocin administration in older men modulates functional connectivity during animacy perception
Aging Brain. 1 [DOI] 10.1016/j.nbas.2021.100023.
2021
Chronic Pain is Associated With Reduced Sympathetic Nervous System Reactivity During Simple and Complex Walking Tasks: Potential Cerebral Mechanisms
Chronic Stress. 5 [DOI] 10.1177/24705470211030273. [PMID] 34286166.
2021
Identification of Negative BOLD Responses in Epilepsy Using Windkessel Models
Frontiers in Neurology. 12 [DOI] 10.3389/fneur.2021.659081. [PMID] 34690906.
2020
Cortical Thickness Mediates the Association Between Self-Reported Pain and Sleep Quality in Community-Dwelling Older Adults
Journal of Pain Research. Volume 13:2389-2400 [DOI] 10.2147/jpr.s260611.
2020
Modeling functional resting-state brain networks through neural message passing on the human connectome
Neural Networks. 123:52-69 [DOI] 10.1016/j.neunet.2019.11.014.
2019
EECoG-Comp: An Open Source Platform for Concurrent EEG/ECoG Comparisons—Applications to Connectivity Studies
Brain Topography. 32(4):550-568 [DOI] 10.1007/s10548-019-00708-w. [PMID] 31209695.
2019
Epilepsy Focus Localization in Patients Utilizing BOLD Differences Related to Regional Metabolic Dynamics
Open Journal of Radiology. 09(03):163-175 [DOI] 10.4236/ojrad.2019.93015.
2019
Mapping Brain Activity with Electrocorticography: Resolution Properties and Robustness of Inverse Solutions
Brain Topography. 32(4):583-598 [DOI] 10.1007/s10548-018-0623-1.
2019
Validating Non-invasive EEG Source Imaging Using Optimal Electrode Configurations on a Representative Rat Head Model
Brain Topography. 32(4):599-624 [DOI] 10.1007/s10548-016-0484-4.
2018
Histological Characterization of the Irritative Zones in Focal Cortical Dysplasia Using a Preclinical Rat Model
Frontiers in Cellular Neuroscience. 12 [DOI] 10.3389/fncel.2018.00052. [PMID] 29867355.
2018
waveCSD: A method for estimating transmembrane currents originated from propagating neuronal activity in the neocortex: Application to study cortical spreading depression
Journal of Neuroscience Methods. 307:106-124 [DOI] 10.1016/j.jneumeth.2018.06.024. [PMID] 29997062.
2017
Spatio Temporal EEG Source Imaging with the Hierarchical Bayesian Elastic Net and Elitist Lasso Models
Frontiers in Neuroscience. 11 [DOI] 10.3389/fnins.2017.00635. [PMID] 29200994.
2015
Tensor Analysis and Fusion of Multimodal Brain Images
Proceedings of the IEEE. 103(9):1531-1559 [DOI] 10.1109/jproc.2015.2455028.
2011
An in vivo MRI template set for morphometry, tissue segmentation, and fMRI localization in rats
Frontiers in Neuroinformatics. 5 [DOI] 10.3389/fninf.2011.00026. [PMID] 22275894.
2011
Automated Discrimination of Brain Pathological State Attending to Complex Structural Brain Network Properties: The Shiverer Mutant Mouse Case
PLoS ONE. 6(5) [DOI] 10.1371/journal.pone.0019071. [PMID] 21637753.
2011
Covert face recognition without the fusiform-temporal pathways
NeuroImage. 57(3):1162-1176 [DOI] 10.1016/j.neuroimage.2011.04.057.
2010
White matter architecture rather than cortical surface area correlates with the EEG alpha rhythm
NeuroImage. 49(3):2328-2339 [DOI] 10.1016/j.neuroimage.2009.10.030.
2009
Approximate average head models for EEG source imaging
Journal of Neuroscience Methods. 185(1):125-132 [DOI] 10.1016/j.jneumeth.2009.09.005.
2009
Latin American Brain Mapping Network (LABMAN)
NeuroImage. 47(1):312-313 [DOI] 10.1016/j.neuroimage.2009.03.030.
2009
On the EEG/MEG forward problem solution for distributed cortical sources
Medical & Biological Engineering & Computing. 47(10):1083-1091 [DOI] 10.1007/s11517-009-0529-x.
2008
A Bayesian framework to identify principal intravoxel diffusion profiles based on diffusion-weighted MR imaging
NeuroImage. 42(2):750-770 [DOI] 10.1016/j.neuroimage.2008.04.242.
2007
Characterizing brain anatomical connections using diffusion weighted MRI and graph theory
NeuroImage. 36(3):645-660 [DOI] 10.1016/j.neuroimage.2007.02.012.

Contact Details

Phones:
Business:
(352) 273-7180