Phenotyping & Assessment in Neuroscience Laboratory

Welcome to the PAIN Lab. In our lab, we use multiple interdisciplinary and translational research approaches to examine the nervous system factors contributing to the observed inter-individual variability in pain phenotypes in older adults, and pain’s functional consequences including cognitive and mobility impairments.

OUr Research

research focus

Chronic Pain

Chronic pain represents the most prevalent and expensive public health condition in the United States, affecting 100 million people in the United States with annual costs to society estimated at $635 billion dollars. This exceeds the combined costs of cancer, AIDS and heart disease. Importantly, while chronic pain affects individuals of all ages, races, and genders, it disproportionately impacts members of some population groups.

Evidence suggests that chronic pain is more prevalent and disabling in older adults, but its neurobiological underpinnings have not been elucidated.
Video By Juan Wiswell

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The NEPAL Study

This project examines the different factors as they relate to the aging brain, including pain sensitivity, walking ability, and thinking and memory.

brain imaging

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UCOPE

Do you have knee pain more days than not? This project examines the effects of Oxytocin on chronic pain in older adults with knee osteoarthritis.

UCOPE Study

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PRICE Studies

The Pain Research & Intervention Center of Excellence has three main research dimensions including basic research, human clinical research and translational research from animal to human models.

UF CTSI

principal investigator

Associate PROFESSOR AND Director of Training

Yenisel Cruz-Almeida, Ph.D., MSPH

As a clinical neuroscientist, my research interests are related to understanding age-related pain perception and modulation in humans. Using multiple interdisciplinary and translational approaches, my research examines nervous system factors contributing to the observed inter-individual differences in pain phenotypes and its functional consequences including cognitive and mobility impairments.

Dr. Yenisel Cruz-Almeida

Laboratory news & Media

Listen to the new PRICE of Pain Podcast episode…

Category: Featured Content

Dr. Cruz-Almeida is the featured guest on the second episode of the Price of Pain…

Dr. Cruz-Almeida on the PRICE of Pain podcast

PRICE Journal Club Thursday, July 1st 11:30-1:00

Category: Featured Content

Please join Dr. Yenisel Cruz-Almeida for the PRICE Journal Club as she discusses the journal article by Boehnke et al. on CBD as a substitute for…

People attending a journal club

New Publication by Dr. Cruz-Almeida

Category: Featured Content

New article on pain severity and interference in different Parkinson’s Disease cognitive phenotypes.

Dr. Yenisel Cruz-Almeida

Cruz-Almeida Laboratory

Media Appearances

Research by Dr. Cruz-Almeida and the PAIN laboratory has been featured throughout the country.

The South Florida Sun-Sentinel wrote about how Dr. Cruz-Almeida's research shows that chronic pain, left untreated, can cause the brain to show signs of aging.
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PHENOTYPING and ASSESSMENT IN NEUROSCIENCE

PAIN Lab

Work in our lab is generously supported by the University of Florida, the National Institutes of Health, and the McKnight Research Foundation.